Istenhegyi Genetic Diagnostics Center
The Istenhegyi Genetic Diagnostics, Gynecological and Family Planning Center was established in 2001 by Hungarian experts. At the beginning, our main activities included the study of the genetic causes of infertility and the laboratory and clinical diagnosis of Lyme disease.
We started to provide screening for fetal disorders in 2003. Our Institute was the first to use the four-part test and the integrated test from blood samples in Hungary, which were the most efficient screening tests for Down syndrome at that time. As testing methods developed, an earlier screening test became available and, in 2004, our Institute was the first to perform screening for Down syndrome based on a combined test that can be used in the first trimester, which is a screening test with an exceptional efficiency that includes a high-accuracy ultrasound test and a maternal blood test.
Before 2013, we performed over 30,000 combined screening tests, supplemented by screening tests carried out in the second trimester, if necessary. Our efficiency complies with highest international requirements: our tests showed an efficiency of 95% with a rate of false positives of only 2.5%.
In 2012, 9% of the mothers in Hungary were tested by the Istenhegyi Genetic Diagnostics Center using one of these screening tests. This year, one third of the fetuses with Down syndrome were diagnosed during pregnancy by the Istenhegyi Genetic Diagnostics Center.
Our Institute is equipped with state-of-the-art laboratory equipment, so the screening tests are carried out using high-accuracy automatic devices and, if necessary, we can also perform a fetal chromosome test. In the case of a chorionic villus test, the results are also confirmed using molecular genetic testing methods in addition to traditional chromosome testing.
After May 2013, by adding the BGI NIFTY test to our methods, we can offer a full-range screening and diagnostic set to the future mothers who request our services.
In addition to screening for infertility and fetal abnormalities, the Genetic Diagnostics Center is the only organization in Hungary that performs fetal genetic tests for monogenic diseases and chromosome abnormalities.
In 2013, the Istenhegyi Genetic Diagnostics Center started to perform mutation determinations on oncology samples necessary for mutation-specific therapy, which can be used to identify the most efficient antitumor therapy. In addition to these tests, we also perform tests such as screening for predispositions, tissue and cytology diagnostics, viral and bacterial diagnostics and full-range pregnancy care.