More than 5.000.000 tests worldwide
Safe
Non-invasive, no risk of miscarriageThe test is performed without posing any risk to the baby
Unlike invasive tests, NIFTY test does not require inserting a needle through the abdomen which poses a risk of miscarriage.
Precise
Scientifically documented evidence for >99% accuracy in cases of trisomies>99% negative prediction value
This means that if NIFTY test is negative, we can be sure by that value about no Down, Edwards or Patau syndrome is present at the baby
Popular
5.000.000 + NIFTY™ tests was performed worldwide until todayNIFTY™ test is the most widely used prenatal test
No other non-invasive prenatal test (NIPT) was performed as widely as NIFTY™ test thanks to the extraordinary reliability of this test
Quick
Results can be obtained after 5-7 workdays after the sample was submitted to the laboratory*It is really that quick
We obtain 1 cm3 maternal blood after a quick and painless blood collection. 18 types of syndromes can be detected from this blood sample and the sex of the fetus also can be identified
*In cases of samples obtained from our rural partners this time can be longer. In some cases the obtained sample will be the subject of further examinations which requires more time but this does not affect the price of the test.
What is NIFTY™ test?
NIFTY™ (Non-Invasive Fetal TrisomY test) is a simple, safe and extraordinarily precise prenatal test which measures the risk of Down, Edwards and Patau syndromes with >99% sensitivity and can also be used to screen other trisomies, sex chromosome abnormalities and microdeletion/microduplication syndromes. The test can be performed after the 10th pregnancy week. 94 types of chromosomal abnormalities can be tested and the sex of the fetus can be also identified.
How NIFTY™ test works?
During pregnancy, fetal DNA enters into maternal bloodstream. Next-generation technology makes it possible to analyze free fetal DNA segments that are present in maternal blood in order to identify chromosomal abnormalities. NIFTY™ test requires only 10 ml maternal blood sample and blood collection can be performed during the 10th pregnancy week.
What types of abnormalities can be detected with NIFTY™ test?
| Trisomies | Other trisomies | Numerical abnormalities of sex chromosomes |
|---|---|---|
| Down syndrome (Trisomy 21) | Trisomy 9 | Turner syndrome (X monosomy) |
| Edwards syndrome (Trisomy 18) | Trisomy 16 | Klinefelter syndrome (XXY) |
| Patau syndrome (Trisomy 13) | Trisomy 22 | Triple X syndrome (XXX) |
| Jakob syndrome (Double Y, XYY) |
| Deletion and duplication syndromes | |
|---|---|
| 7q | 7q deletion syndrome |
| 18q | 18q deletion syndrome |
| 9p | 9p deletion syndrome |
| 14q11-q22 | 14q11-q22 deletion syndrome |
| 1 p36 | 1 p36 deletion syndrome |
| 6q11-q14 | 6q11-q14 deletion syndrome |
| 8q12.2-q21.2 | 8q12.1-q21.2 deletion syndrome |
| Xq21 | Xq21 deletion syndrome |
| 1q41-q42 | 1q41-q42 deletion syndrome |
| 6q24-q25 | 6q24-q25 deletion syndrome |
| 3q22-q24 | Dandy-Walker syndrome |
| 18p | 18p deletion syndrome |
| 10q26 | 10q26 deletion syndrome |
| 3pter-p25 | 3pter-p25 deletion syndrome |
| 2p12-p11.2 | 2p12-p11.2 deletion syndrome |
| 5q14.3-q15 | 5q14.3 deletion syndrome |
| 13q14 | 13q14 deletion syndrome |
| 10q23 | 10q22.3-q23.2 deletion syndrome |
| 15q26-qter | Levy-Shanske syndrome |
| 15q26-qter | 15q26-qter deletion syndrome |
| 6pter-p24 | 6pter-p24 deletion syndrome |
| 2q31 | Split-hand/foot malformation 5 |
| Xq27.3-q28 | Xq27.3-q28 duplication syndrome |
| 2q37.1-q37.3 | Holoprosencephaly 6 |
| Xp21 | Xp21 deletion syndrome |
| 5p | Cri du Chat syndrome |
| 11p13-p12 | WAGRO syndrome |
| 4q21 | 4q21 deletion syndrome |
| 17p12-p11.2 | Yuan-Harel-Lupski syndrome |
| 22q11 | Cat-Eye syndrome |
| 11q23 | Jacobsen syndrome |
| 10p14-p13 | DiGeorge syndrome 2 |
| 8q24.11-q24.13 | Langer-Giedion syndrome |
| 2p16.1-p15 | 2p16.1-p15 deletion syndrome |
| 4q32.1-q32.2 | 4q32.1-q32.2 triplication syndrome |
| 16p12.2-p11.2 | 16p12.2-p11.2 deletion syndrome |
| Xp11.23-p11.22 | Xp11.23-p11.22 duplication syndrome |
| 2q31.1 | 2q31.1 duplication syndrome |
| 2q33.1 | 2q33.1 deletion syndrome |
| Xq28 | Xq28 deletion syndrome |
| 22q11.2 | 22q11.2 duplication syndrome |
| 16pter-p13.3 | 16p deletion syndrome |
| 16p13.3 | 16p13.3 deletion syndrome |
| 16p12.2-p11.2 | 16p11.2-p12.2 microduplication syndrome |
| 5q12 | 5q12 deletion syndrome |
| 1p32-p31 | 1p32-p31 deletion syndrome |
| 1p31.3 | 1p31 duplication syndrome |
| 16q22 | 16q22 deletion syndrome |
| 14q22.1-q22.3 | Frias syndrome |
| 15q11 | 15q11-q13 duplication syndrome |
| 6q27 | CHDM |
| 15q14 | 15q14 deletion syndrome |
| 17q12 | 17q12 duplication syndrome |
| 17q12 | 17q12 deletion syndrome |
| 3q29 | 3q29 duplication syndrome |
| 3q29 | 3q29 deletion syndrome |
| 8q22.1 | 8q22.1 duplication syndrome |
| 8q22.1 | 8q22.1 deletion syndrome |
| 15q11.2 | Prader-Willi/Angelman syndrome |
| 21q22.3 | Holoprosencephaly 1 |
| 11p13 | WAGR syndrome |
| 7q11.23 | 7q11.23 deletion syndrome |
| 7q11.23 | 7q11.23 duplication syndrome |
| 2018.11.02 23:00 | Potocki-Shaffer syndrome |
| 15q26.1 | HCD |
| Xq22.3 | Xq22.3 telomeric deletion syndrome |
| 4p16.3 | Wolf-Hirschhorn syndrome |
| 17q21.31 | 17q21.31 duplication syndrome |
| Xp11.3 | Xp11.3 deletion syndrome |
| 3q13.31 | 3q13.31 deletion syndrome |
| 8p23.1 | 8p23.1 deletion syndrome |
| 8p23.1 | 8p23.1 duplication syndrome |
| 12q14 | 12q14 microdeletion syndrome |
| 17q23.1-q23.2 | 17q23.1-q23.2 deletion syndrome |
| 17p11.2 | Potocki-Lupski syndrome |
| 17p11.2 | Smith-Magenis syndrome |
| 17p13.3 | 17p13.3 duplication syndrome |
| 17p13.3 | 17p13.3 deletion syndrome |
| 19q13.11 | 19q13.11 deletion syndrome |
| 2q34-q36 | 2q35 duplication syndrome |
| 15q25 | 15q25 deletion syndorme |
| 22q11.2 | 22q11.2 deletion syndrome |
| 22q11.21 | DiGeorge syndrome |
Who do we recommend a NIFTY™ test?
Some women have a bigger chance of carrying a fetus who has some type of genetic abnormality. Performing a NIFTY test can be recommended in cases below:
NIFTY test can also be recommended to those pregnant women who want to have a more reliable test than the combined test.
Comparing NIFTY™ test and other conventional prenatal screening tests
| Method | Invasive/Non-invasive | Pregnancy (week) | Pregnancy (week) |
|---|---|---|---|
| Biochemical screening test of the maternal serum | Non-invasive | Week 11-13+6 Week 14-20 | False positive rate: 5% Detection rate: 60-70% |
| Fetal nuchal translucency measurement | Non-invasive | Week 11-13+6 | False positive rate: 3% Detection rate: 60-80% |
| Combined test | Non-invasive | Week 11-13+6 | False positive rate: 2.5-3% Detection rate: 90-93% |
| Chorionic villus sampling/amniocentesis | Invasive | Week 10-20/Week 16-20 | Miscarriage rate: 0.5-1% Detection rate: >99% |
| NIFTY™ test | Non-invasive | Week 10-18 | No risk of miscarriage False positive rate: < 0.1% detection rate: >99% |
What is the price of NIFTY™Pro test?
The recommended price of NIFTY™-pro test from July is 225.000 HUF.
Besides NIFTY™ test az ultrasound exam may also be needed which costs 33.000 HUF.
For reasons described earlier, our centre recommends performing a combined test also for those who choose NIFTY™-pro test. In this case we offer the combined test FREE OF CHARGE. (Only the price of NIFTY™ test and the price of the genetic ultrasound have to be paid.)
In cases of twin pregnancies, the price of NIFTY test is cheaper, we offer it for 195.000 HUF from July 2022.
Why should I choose NIFTY™ test?
NIFTY™ test is currently the leading non-invasive prenatal test.
The advantages of NIFTY™ test
NIFTY™ test is extremely precise
During clinical trials, the test detected fetal trisomies with a >99.9% accuracy rate
Negative prediction value (NPV)
The reliability of a negative test result, which means the probability that if the test result is negative than the fetus is really healthy
Specificity
The probability of a negative NIFTY™ test result in the case of a pregnant woman whose fetus is healthy. So specificity illustrates the reliability of NIFTY™ test when detecting those in whom there is no detectable chromosomal abnormality.
Sensitivity
The probability of a positive NIFTY™ test result in the case of a pregnant woman in whose fetus there is a chromosomal abnormality is present. Sensitivity characterizes the reliability of NIFTY™ test when detecting those in whom there is an abnormality is present.
With NIFTY™ test you can be reaassured
In case you perform a NIFTY™-pro test and your result is positive, you will not be left alone.
Free supplementary test
If the test result is “high risk”/”positive”/”detectable” for any tested abnormality then Istenhegyi Genediagnostic Centre offers a free chorionic villus sampling/amniocentesis examination and a free chromosome analysis from this sample plus other free supplementary tests (for example FISH).
Warning: in case of a twin pregnancy NIFTY test will cover the testing of 21, 18 or 13 trisomies.
The professional background of NIFTY™ test are guaranteed by renowned companies
Istenhegyi Genediagnostic Centre
At our centre we are performing fatal abnormality screenings since 2003. We were the first in Hungary to introduce Down syndrome screening based on combined tests performed at the first trimester. Our performance is in alignment with the highest international standards. In 2012, Istenhegyi Genediagnostic Centre performed some kind of screening test in 9% of Hungarian pregnant women. In this year, one-third of fetuses with Down syndrome were diagnosed at our centre.
Since May 2013 we included BGI’s NIFTY™-test in our fetal test arsenal so since then we can offer a complete screening and diagnostic panel to all the pregnant women who are visiting us. Our centre has the most up-to-date laboratory devices.
Besides that we offer a complete pregnancy care, photorealistic 4D/5D ultrasound examinations (“Baby cinema”).
For more information please visit our homepage: http://gendiagnosztika.hu
BGI, developer of NIFTY™ test
BGI is one the world’s biggest company dealing with genetic research, tests and services where we apply the latest results of human genetic research in our daily work. BGI focuses on the clinical applications of genetic technologies in order to reduce the number of perinatal abnormalities and other diseases.
BGI was founded on 09.09.1999 with a centre in Shenzen (China). Now we hot offices nearly everywhere around the world – in the US, in Europe and in Asia. Our mission is to achieve the best in every field of our work, to be as productive as we can be and to be highly accurate.
We are dedicated to improve people’s quality of life by improving the effectiveness of biological research while improving agriculture, environmental protection and healthcare.
Our patients’ satisfaction is highly important to us!
Based on the feedback we receive from pregant women who visited us, we are constantly improving our services.
“I wish the best to all team members, keep going!”
“Very professional and friendly team!” They could help me immediately in another health-related question of mine. If I wouldn’t be staying abroad, I should have continued fetal screening tests at your centre.” – L. Edit
“Physicians who perform ultrasound screening are maximally professional and they all do an excellent job.”
“Giving a 10 point score means for me that I was totally satisfied with the physicians’ professional knowledge and their helpfulness. I got answered to all my questions.”
“I’m thankful for all the resiliency and helpfulness which made me easier to get an appointment with a short deadline even from abroad and an excellent service then.”
“They were very educated, I received their phone call in two weeks as they promised and then I also received their letter in a short time.”
“I’ve never been to Istenhegyi Genediagnostic Centre personally but I’m very happy that they organized the transfer of my blood sample from my home country.”
Where can I get the NIFTY™ test?
Our central address: Istenhegyi Genediagnostic Centre
1125 Budapest, Zalatnai utca 2.